Anorexia nervosa (AN) is a complex psychiatric disorder associated with alterations to satiety, activity, and self-perception that results in severe mental distress and malnourishment (Sibeoni et al., 2017). Cognitive behavioural therapy and weight rehabilitation are the first-line treatments for AN, as there are still no approved pharmacotherapies for the disorder (Wonderlich, Bulik, Schmidt, Steiger, & Hoek, 2020). Unravelling the biological complexity of AN onset and its clinical course will be key to developing more effective interventions and improving clinical management.
