Subjects with depression were identified through self-report in web-based surveys. A total of six survey data sources were used to compose the depression phenotype: (Your Medical History survey: 2009–2013) “Have you ever been diagnosed by a doctor with any of the following psychiatric conditions?” (options for Depression: Yes, No, I don’t know)(Research Snippet: 2010–2014) “Have you ever been diagnosed with clinical depression?” (answers: Yes, No, I’m not sure)(Health Intake survey, unbranched: 2014–2015) “Have you ever been diagnosed with or treated for any of the following conditions?” (options for Depression: Yes, No, I’m not sure)(Health Intake survey, branched: 2013) 4a“Have you ever been diagnosed or treated for any of the following conditions?” (“A mental health or psychiatric condition”: Yes, No, I’m not sure)4b“What mental health problems have you had? Please check all that apply” (check box: Depression)(Health Profile survey: 2015–2016) 5a“Have you ever been diagnosed with or treated for any of the following conditions? Anxiety, Attention deficit disorders, Bipolar disorder / manic depression, Depression, Eating disorder (such as anorexia or bulimia)” (answers: Yes, No, I’m not sure)5b“Have you ever been diagnosed
