McGue, & Iacono, 2016). Although we obtained one genome-wide significant association, it has no obvious connection with brain activity, and unless replicated, it cannot be considered meaningful. Thus, decomposing P300 into simpler time-frequency components did not produce a fundamentally different result, and in general we suspect that refining endophenotypes or searching for supposedly simpler endophenotypes will not be a silver bullet for finding genes.
