embryonic and the adolescence stages (Fig. 5a). Moreover, the numbers of edges in the networks for all four embryonic brain regions and three of the four adolescence regions (except subcortex) were significantly greater than those of the networks derived from randomly chosen genes (Fig. 5b). These results indicate that a subset of the 22q11.2 DEGs are significantly co-expressed and likely functionally connected to two key stages of brain development.
