While the association between rheumatic fever – particularly its neurological manifestation, Sydenham's chorea –, OCD, and TD/CTD has been well established, the link with other classic AD is far less clear.13-16 The previous literature has been scarce and severely limited by methodological issues, such as the study of small sample sizes mainly recruited from specialist clinics, the use of cross-sectional designs, lack of blind assessors, lack of control groups, and the use of self-report measures known to have poor psychometric properties.13
