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Chunk #28 — The Nociceptin/Orphanin FQ as a target for the treatment of alcohol abuse

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Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond.
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These findings point toward the possibility that these effects of buprenorphine are mediated by activation of NOP receptors. Altogether, these data provide strong rationale for the development of N/OFQ receptor agonists as new therapeutics for the treatment of alcohol addiction.