To our knowledge, this is one of the first studies to examine the risk of mortality with cannabis and alcohol in people with PD. This interesting finding of decreased mortality risk, specifically in cannabis users, is a novel finding and one that will need replication in larger epidemiological studies. Future research is needed to shed light on the mechanisms of cannabis and its role in decreased mortality in people with PD. There is a growing need to understand the long-term effects of cannabis especially because medical marijuana is legal in many states in USA for chronic debilitating medical conditions. Better understanding the risk of mortality in people who are dually diagnosed will enable the field to better target interventions.