The DGI stage 1 Swedish and Finnish sample consists of 1,464 T2D cases and 1,467 normoglycemic controls. Of these, 2,097 are population-based T2D cases and controls matched for BMI, gender, and geographic origin, and 834 are T2D cases and controls in 326 sibships discordant for T2D1. These samples were genotyped on the Affymetrix GeneChip Human Mapping 500k Array Set, and all included samples had a genotype call rate >0.95. 378,860 autosomal SNPs passed QC criteria (call frequency >0.95, HWE p>10−6 in controls and MAF>0.01 in both population and familial components)1.
