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Chunk #29 — 5. PERTURBATION OF THE GLUTAMATERGIC SYSTEM IN ADDICTED BRAIN

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Gene expression in the addicted brain.
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yes

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the loss of mGluR2 receptor in P rats, but also more readily points to overall neuronal differences between P and NP rats that influence alcohol-drinking behaviors. The gene expression differences between P and NP rats are thus consistent and convergent with their genetic and phenotypic differences and are likely to be influenced by their overall genetic differences or the interaction of Grm2 C407* with other loci.