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Chunk #22 — Discussion

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PROSPER Intervention Effects on Adolescents' Alcohol Misuse Vary by GABRA2 Genotype and Age.
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hold for adolescents of other racial/ethnic backgrounds as well as for adolescents in urban areas. Fourth, although previous findings support the validity of adolescent self-reports of drinking and drunkenness (Smith, McCarthy, & Goldman, 1995), our alcohol use measures were based on youth self-reports, which may be subject to social desirability bias. Fifth, the multicomponent nature of the intervention limits our ability to determine which components were most versus least effective on average, by genotype, or by other pre-existing characteristics. However, both the family- and school-focused intervention components have been previously established as evidence-based interventions (Spoth et al., 2011), providing some assurance that both components are contributing to reduction in alcohol misuse.