difficult to distinguish between genetically mediated factors and those as a result of familial environmental effects in family-based studies, the observations presented here suggest that intergeneration transmission of psychopathology through the maternal line places offspring at very high risk for experiencing psychopathology. This is underscored by the high rate of Drug Abuse and Drug Dependence and MDD seen in early young adulthood. Because the follow up is ongoing, not all offspring have been followed during young adulthood and so the complete picture of this relationship is not currently known.
