excitation and inhibition increase and decrease together during physiological cortical activity (van Vreeswijk and Sompolinsky, 1996), but interference of this relationship appears to be highly disruptive. Highlighting the importance of a proper relationship between excitation and inhibition, is the fact that changes in the weight of excitation or inhibition are accompanied by compensatory effects that preserve the excitability of cortical networks (Turrigiano, 2011).
