subset of autosomal non-imprinted genes (Chess, 2012). Specifically, we hypothesize that a random stochastic process occurring during the reprogramming of individual fibroblasts to generate iPSC clones results in random allelic bias for the expression of chr4p12 GABAA genes. In this model, iPSC allelic expression bias for the chromosome carrying a cis-acting repressive functional variant linked with the rs279858*C-allele would determine Cluster membership for a given iPSC line.
