Although maternal BAP complex proteins are required for the early stages of specifying segmental identity in D. melanogaster, when BRM or other components of the BAP complex are depleted from the zygote, this leads to multiple defects in organ and gamete formation and is lethal in embryos at late stages of development (see ref. 22 for a review), revealing that the roles of the BAP complex extend beyond antagonizing PcG proteins.
