At the time point of the maximum N1 amplitude (435–440 ms after valve activation), socially anxious female participants show stronger brain activations across left and right frontal scalp areas in response to chemosensory anxiety signals than in response to the control stimuli (Fig. 2). The frontal activity starts about 300 ms with a right sided maximum, and about 400 ms after stimulus onset with an additional left sided maximum. The frontal activity vanishes briefly at about 500 ms after valve activation and reappears between 500 and 700 ms with a medial maximum (see Supplementary Material, Video S2). During the entire time period of the CSERP no frontal neuronal sources can be detected in socially anxious females smelling sport sweat. Instead, the chemosensory control stimuli are processed by centrally located neocortical brain areas, between 400 and 600 ms after valve activation (Fig. 2).
