The Reactome Knowledgebase of the molecular details of human biological processes continues to grow in size and scope, notably with the development of tools to annotate the roles of drugs in these processes to yield an integrated description of default human processes and their modulation by drugs. We have implemented a new web feature to recruit experts to participate in our review process and other aspects of curation. New visualization features provide high-quality, downloadable diagrams of individual reactions and an overview of all of our content in a format that should facilitate exploration of gene expression and similar data sets.