that Roache et al. (2008) included three self-report measures of aggression, which were not included in our cluster analysis [nor were they elements in the original cluster analysis conducted by Babor et al. (1992)]. The use of aggression measures to differentiate alcoholism subtypes has important implications for their moderating effects on the response to a serotonergic antidepressant such as sertraline. Buydens-Branchey et al. (1989a) reported that, among EOAs, central serotonergic activity was inversely related to aggression. Thus, inclusion of this behavioral dimension in the derivation of cluster subtypes could increase the utility of the approach.
