We used the UniProt database (www.uniprot.org) and the GeneCards resource (www.genecards.org) to compile a comprehensive list of human transcription factors that accounts for all name multiplicity, synonymity, and redundancy between the abbreviated transcription factor names used by HOCOMOCO (since Uniprot naming is in one-to-one relationship with the HOCOMOCO naming system) and ENCODE. We manually curated this list. We identified 106 (DataSet S1i) transcription factors common to both lists, and all searches for overlaps between HOCOMOCO computational TFBSs and ChIP-seq empirical TFBSs were performed using this list.
