Chunk #45 — DISCUSSION — Is SDPS proneness a common denominator in depression and addiction vulnerability?

Source

Stress vulnerability promotes an alcohol-prone phenotype in a preclinical model of sustained depression.

Embedded

yes

Text

In conclusion, we showed that the SDPS model can be used to screen for depressed individuals with propensity to alcohol abuse and identify those that will develop AUD‐like phenotypes. In turn, this can be used as a starting point for further research into (epi) genetic vulnerability factors, as well as molecular mechanisms that underlie the comorbid phenotype.