K.Y. conceived the project, performed all experiments, and wrote the manuscript; M.I. and M.N. performed nanoLC-MS/MS for drug kinetics; H.T., T.I., and M.M. helped with the iPSC maintenance and EC and pericyte differentiation; T.S. and Y.N. performed nanoLC/MS/MS for DHA; T.K. and H.I. helped with the neuron and astrocyte differentiation; J.K.Y. supervised the experiments.