large, aspiny acetylcholine (ACh) -containing interneurons in the NAc [14]. Cholinergic interneurons have large dendritic arbors and an extensive network of axons that contact many cell bodies and terminals within both the core and shell subdivisions of the NAc [15,16]. Thus, in conjunction with DA inputs from VTA, ACh interneurons can modulate the activity of the GABA projection neurons, the primary output neurons of the NAc [17,18].
