We next tested whether the association between parental EXT PGS and adolescent externalizing behavior was mediated by parental externalizing psychopathology and aspects of parenting. Mediators were tested in separate models. Table 5 summarizes the models testing whether indirect effects of parental EXT PGS (i.e., genetic nurture effects) are mediated via parental externalizing or parenting measures. Among EA participants, there was evidence that parental EXT PGS had an indirect genetic effect on adolescent externalizing behavior through parental externalizing behavior. This indirect effect remained significant after correcting the multiple tests using a 10% false discovery rate (Benjamini & Hochberg, 1995). Parental externalizing accounted for 68% of the variance in the unique association between parental EXT PGS and adolescent externalizing behavior, controlling for the effect of adolescent EXT PGS. There was no evidence that parental EXT PGS had indirect effects on adolescent externalizing behavior through any aspects of parenting examined.
