For the purpose of integrating ERP/ERF and fMRI or investigating the relationship between them, it is particularly important to develop a theoretically-driven approach to interpret the fMRI signals as certain meaningful indices in terms of ERP/ERF. In this regard, we have developed a mathematical model [24] to describe the interactions between stimuli (or tasks), neuronal synaptic currents and BOLD responses. This model allows us to derive the relationship between event-related synaptic responses and BOLD fMRI signals.