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Chunk #7 — MATERIALS AND METHODS — Genotyping and Quality Control

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Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.
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Follow-up genotyping (Phase 3 sample) was performed using a custom Illumina GoldenGate Genotyping Universal-32, 1536-plex microarray. Most SNPs included in the custom array were selected for studies of other phenotypes. Additional SNPs were genotyped individually using the TaqMan method (11).