Chunk #18 — Background — Details of data simulation — 1. Overview of the disease model and ascertainment in the data collection groups

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Construction of the model for the Genetic Analysis Workshop 14 simulated data: genotype-phenotype relationships, gene interaction, linkage, association, disequilibrium, and ascertainment effects for a complex phenotype.

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There were four "groups" that ascertained KPD data. The Aipotu, Karangar, and Danacaa groups ascertained only nuclear families. The NYC group found mostly three-generation pedigrees with at least four affected members.