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Chunk #30 — METHODOLOGICAL ISSUES — Heterogeneity of Depressive Disorders

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Personality and depression: explanatory models and review of the evidence.
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It is important to note, however, that associations between personality and specific subtypes and clinical characteristics do not necessarily indicate etiological heterogeneity. Instead, they could reflect pathoplasticity, in which personality influences symptom presentation and/or course, but the primary etiological process is the same, or they could reflect differential severity of subtypes that results in quantitative differences in their trait profiles.