component analysis (PCA) of genotype data.31, 32 Subjects not genotyped on the HumanOmni1-Quad_v1.0 were genotyped on the Human Core Exome microarray, which contains both exome-focused SNP content and tagging SNPs for genome-wide imputation. Details about the application of quality control procedures to the Human Core Exome microarray data are provided in Supplemental Methods. Genotype data are being released via the National Institutes of Health (NIH) dbGAP platform (accession number phs000425.v1.p1).
