The intracellular kinases such as PKA and GSK3β are located at both pre- and post-synaptic sites, which regulate neuronl function including excitability and neurotransmitter release (Zhu et al., 2010; Park et al., 2014). GSK3β-mediated inhibition of presynaptic glutamate release may contribute to ethanol-induced suppression of γ oscillations, due to ethanol-induced activation of GSK3β (Zhu et al., 2010).
