Limitations of the present study include the differences in the studied groups (community sample of young adults vs middle-aged inpatients) and the differences in symptom assessments (SCID-II interview vs self-report SCID-II Screen questionnaire). Another limiting factor in the interpretation of our results is the high rate of comorbid conditions, such as substance abuse in the US young adult sample or anxiety disorder in the Hungarian patient sample. Therefore, further analyses are required to assess the genetic effects on specific BPD symptoms in a wide range of subjects, probably involving healthy individuals without confounding comorbid conditions.
