The results of gene-wise and gene set analyses are described in the Supplementary Results. The tissue-specificity of associated genes differed minimally between the analyses (Supplementary Table 9). All brain regions were significantly enriched in all analyses, and the pituitary was also enriched in combined MDD and PGC BD (p < 9.43×10−4, Bonferroni correction for 53 regions, Supplementary Table 9). Results from down-sampled MOOD and down-sampled MDD were generally consistent with the main analyses, except spinal cord was not enriched in either, nor was the cordate in the down-sampled MDD analysis.
