of the observed associations. For example, an intronic SNP, rs3129934, on chromosome 6 that is a cis-acting eQTL for multiple HLA transcripts with a high eQTL functional score (24.9) shows the strongest association with T1D in the MHC region in the WTCCC study [11] and is also the SNP most strongly associated with increased risk for multiple sclerosis (MS) in a pooling-based GWAS [18].
