All experiments, where only representative pictures are shown, were performed successfully at least two times. Statistics (except those shown for the evaluation of scRNA-Seq data) were performed with GraphPad Prism 9.3.1 using the Mann–Whitney U-test (two-tailed) for non-parametric data or one-way ANOVA. Data are presented as mean values, including standard error of the mean (SEM). p-values of *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 were considered statistically significant.
