Chunk #52 — Methods — Statistical analyses — Cross disorder GWAS for evaluation of the general association of rs56372821 with psychiatric disorders

Source

Genome-wide association study implicates CHRNA2 in cannabis use disorder.

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yes

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We re-did the cross-disorder GWAS excluding all individuals with a CUD diagnosis (removing 2,290 individuals from the case group and 97 individuals from the control group), reducing the sample size to 32,716 cases and 16,269 controls. The GWAS was conducted using the PCs from PCA and wave as covariates.