Association 2000). The subpopulation analyzed in the current study included all cases with a diagnosis of alcohol dependence or alcohol abuse (n = 512) and their sex- and age-matched controls having no mental disorders (n = 511). There were 99 women in both groups. Of the 512 cases, 414 (326 men/88 women) had a diagnosis of alcohol dependence, and 89 (78 men/11 women) had a diagnosis of alcohol abuse only. In addition, there were nine individuals with alcohol abuse diagnosis, but who lacked information concerning the dependence status; these cases were included in the analyses when considering the combined group of alcohol-dependent and alcohol abuse cases, but were excluded from the analyses focusing on the dependence and abuse subcategories. Genotyping results were obtained from 503 cases and 506 controls.
