were appetite and weight, decreased in typical and increased in atypical. Of note, LCA-subtypes do not necessarily overlap with DSM classification of melancholic and atypical. The third class was labeled “moderate” and was characterized by lower severity. For the analyses based on LCA-subtypes we initially included 1,176 patients (~80% of those available) whose class could be assigned with confidence (average posterior probability > 0.7, indicating adequate separation and classification precision(30)). Proportions of the subtypes were 19.4% for severe typical, 21.3% for severe atypical and 59.3% for moderate.
