The frequency of marker alleles and genotypes in cases and controls were compared using Fisher's exact test, as implemented in R v2.7.0 (http://www.R-project.org). This test was preferred over a parametric test since there were numerous instances of small cell counts in the tables. This test was also used to estimate allelic odds ratios (OR) with their corresponding 95% confidence intervals. The most significant results were also evaluated using the chi-square test and no substantial differences were found. An uncorrected P-value of 0.01 was chosen as the threshold for point-wise significance for the association tests.
