based on TD between GTEx-cerebellum and GTEx-blood (Supplementary Fig. 13). Note that these results do not contradict the observation from a recent study that eQTLs detected in specific tissues in GTEx tend to be most enriched among the variants predicted to be functional in relevant REMC tissues28. There were some examples where the cis-eQTLs with tissue-specific effects in brain and blood were located in enhancers (Supplementary Fig. 14). These examples, however, were rare because only 14 of the 308 eQTLs with Pdifference < 0.05/1388 were located in enhancers and only 4 of the 14 enhancers appeared to be tissue specific.
