Most GABAA receptor subunit genes (6 of 8) showed decreased expression in the alcohol group, but Gabra6, which is expressed more highly than other GABAA subunits in this tissue, showed increased expression. The 5 serotonin-related genes that were differentially expressed all had reduced expression. Similarly, all 6 differentially expressed acetylcholine receptor-related genes and all 4 of the glycine receptor-related genes had reduced expression in the drinking animals. Expression of dopamine receptors Drd2 and Drd5 was decreased in the alcohol drinking group. One highly expressed adenosine receptor (Adora1) was increased 1.4-fold. Four purinergic receptors also had altered gene expression.
