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Chunk #45 — Comment — Limitations

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Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence.
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Finally, despite much effort it was not, for technical reasons, possible to obtain 95% confidence intervals on all the parameters in our best-fit model. Plausible confidence intervals were obtainable by permutation for the first genetic factor and the criterion-specific environmental loadings. As expected, these parameters were known with modest accuracy, with a mean span of confidence intervals of 0.25 and 0.19, respectively.