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Chunk #14 — 2. Methods — 2.6. Statistical analyses

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Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.
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Logistic regression analyses with attempted suicide as the dependent variable were undertaken using JMP 7 software and yielded likelihood ratio (L-R) χ2 results. Backward stepwise regression was performed with predictor variables being eliminated from the model in an iterative process if the level of significance was p > 0.1. The continuous CTQ score and European ethnic factor score and the dichotomous variables: age, sex and substance dependence diagnosis were initially included as predictor variables. Age and sex had no significant effects in any model. Substance dependence and the continuous CTQ score were included in all models since they had a significant effect.