of the Effects of Alcohol (SRE) questionnaire. A linkage analysis using these responses as the phenotype, revealed loci on chromosomes 6q25.2 and 9p24.1 that had a LOD score greater than 3.0. Like the EEG studies previously described, these studies provide support for the use of an individual's sensitivity to a given substance as an important endophenotype for alcohol and other substance use disorders in Native Americans as well as in general population samples [42].
