Recently, heterogeneity in the responsivity of GABAergic transmission to eCB signaling within the LA and BA divisions of the BLA has been demonstrated. Specifically, Win 55212-2-induced depression of eIPSCs is significantly greater in the BA than the LA, an effect related to higher expression of the CB1 receptor on inhibitory axon terminals in the BA relative to the LA (Yoshida et al., 2011). As such, this difference in CB1 receptor expression results in an increase in DSI magnitude in the BA compared to LA (Yoshida et al., 2011).
