The classification accuracy was 76.67% as the RF algorithm correctly classified 23 out of 30 subjects in each group. The model identified 14 DMN connections, two neuropsychological variables (memory span and total correct scores of the forward condition of the VST), and all four impulsivity scores as significantly contributing to classifying individuals into either the AUD or CTL group (Table 3 and Figure 2 and Figure 3). Among the significant DMN connections, the AUD group showed hyperconnectivity in three DMN connections across bilateral ACC and bilateral PFC (L.ACC–L.PFC, L.ACC–R.ACC, and R.ACC–R.PFC) as well as in two connections across bilateral PCC and left IPL (L.PCC–L.IPL and R.PCC–L.IPL), while showing hypoconnectivity in rest of the connections across the anterior–posterior and interhemispheric regions (L.PCC–R.ACC, R.PCC–R.ACC, L.PCC–R.PFC, L.ACC–L.LTC, R.ACC–L.LTC, L.PFC–R.LTC, L.IPL–R.PFC, R.IPL–L.LTC, and R.PFC–R.LTC) (see Figure 4 and Table 3). AUD individuals also showed relatively poorer visuo-spatial memory performance and higher impulsivity than controls.
