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Chunk #1 — Introduction

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Lipid environment modulates the development of acute tolerance to ethanol in Caenorhabditis elegans.
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observed during a single drug exposure and is measured as a greater behavioral impairment at the beginning of a drinking session than the impairment observed at a similar blood ethanol concentration during the falling phase of blood alcohol concentration. In C. elegans, we observe AFT during a single ethanol exposure, in which the animals recover their ability to move despite no decrease in internal ethanol concentration [4].