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Chunk #7 — Subjects and Methods — Subjects

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GABRA2 markers moderate the subjective effects of alcohol.
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using the 90-day Time Line Follow Back (TLFB) (Sobell et al., 1988). To minimize adverse reactions to the alcohol administration, participants had to report at least two drinking episodes in any 30-day period during the 90 day TLFB and at least one of these episodes had to entail two or more drinks for women and three or more drinks for men. In addition, subjects could not report drinking more than 28 alcoholic drinks per month for women or 56 alcoholic drinks for men (i.e., less than NIAAA guidelines for heavy/hazardous drinking). Subjects with heavy/hazardous drinking or current alcohol use disorders were excluded because of the potential for such subjects to have already undergone a change in alcohol sensitivity due to heavy alcohol exposure.