Subjects were recruited and assessed using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA; Bucholz et al., 1994), the Timeline Followback interview (TFLB; Sobell et al., 1986) for habitual drinking, and the Alcohol Use Disorders Identification Test (AUDIT; Saunders et al., 1993). Two samples of non-dependent heavy drinkers (HD) were acquired (Table 1), 14 of whom were family history positive for alcoholism (HD-FHP; at least two first or second degree relatives with probable alcoholism on the SSAGA family history module, excluding mothers to preclude possible fetal alcohol effects) and 12 of whom had no known family history of alcoholism (HD-FHN). None had been treated for alcohol disorders, had evidence of Axis-I psychiatric disorders, had neurological disorders of the brain, or failed olfactory screening. While differing in family history, there were no significant group differences in age (range 21 – 31 across all subjects), education, recent drinking (drinks per week and drinking day, heavy drinking days defined as >3/>4 for women/men), scores on the AUDIT, age of first and regular drinking, gender, and percentage of smokers (see Table 1). Although
