Chunk #21 — Polygenic Risk Scores: A Bridge Between Population Variation and Individual Differences — PRS Practicalities — STEP 4: Calculate PRS for each individual in your sample.

Source

Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences.

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Software programs including PLINK (Purcell et al., 2007, Chang et al., 2015) and integration with PRSice (Euesden et al., 2015b) facilitate PRS calculation.