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Chunk #14 — RESULTS

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Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.
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The GWA results of the five temperaments are displayed in Figure 1. Genomic regions of interest were defined as those with at least two SNPs with p<10−4 and adequate support for association from surrounding SNPs with at least two additional SNPs with p<10−3, all within 100kb. Several such regions were identified across the five temperaments, and the regions meeting these criteria that were located within or near genes are indicated. SNPs with p<10−4 within regions reaching GW significance are detailed in Table 2, and a complete listing of all SNPs with p<10−4 provided in Table S2 with the results of the results of the case-control analysis provided as a comparison to the results for the relevant temperament.