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Chunk #33 — Methods — Depression GWAS Data

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Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
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For the discovery analysis, we used summary statistics from 500,199 participants in the latest GWAS of depression by Howard and colleagues10 that did not include 23andMe participants and were of European descent. Of these, 361,315 were from the UK Biobank and 138,884 from the Psychiatric Genetics Consortium26. Approximately 34% of the participants had depression.