Chunk #20 — Materials and methods — Statistical Analyses — GWAS

Source

Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15.

Embedded

yes

Text

We adopted a GWAS significance threshold at p = 4.2 × 10−7, which was derived by Freimer and Sabatti (22) based on a gene-wise approach, and subsequently modified by Lencz et al. (23) taking into account a more accurate estimate of the total number of genes in the human genome.